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Did Finishing the Drosophila Genome Legitimize Open Access Publishing?
I’m currently reading Glyn Moody‘s (2003) “Digital Code of Life: How Bioinformatics is Revolutionizing Science, Medicine, and Business” and greatly enjoying the writing as well as the whirlwind summary...
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Will the Democratization of Sequencing Undermine Openness in Genomics?
It is no secret, nor is it an accident, that the success of genome biology over the last two decades owes itself in large part to the Open Science ideals and practices that underpinned the Human Genome...
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Top N Reasons To Do A Ph.D. or Post-Doc in Bioinformatics/Computational Biology
For the last few years I’ve given a talk to incoming Ph.D. students in Molecular Biology on why they should consider doing Computational Biology research. I’m fairly passionate about making this pitch,...
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The Cost to Science of the ENCODE Publication Embargo
The big buzz in the genomics twittersphere today is the release of over 30 publications on the human ENCODE project. This is a heroic achievement, both in terms of science and publishing, with many...
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On The Neutral Sequence Fallacy
Beginning in the late 1960s, Motoo Kimura overturned over a century of “pan-selectionist” thinking in evolutionary biology by proposing what has come to be called The Neutral Theory of Molecular...
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Directed Genome Sequencing: the Key to Deciphering the Fabric of Life in 1993
Seeing the #AAASmtg hashtag flowing on my twitter stream over the last few days reminded my that my former post-doc advisor Sue Celniker must be enjoying her well-deserved election to the American...
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Incentivising open data & reproducible research through pre-publication...
Yesterday Ewan Birney posted a series of tweets expressing surprise that more people don’t take advantage of ENA’s programmatic access to submit and store next-generation sequencing (NGS) data to EBI,...
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